Immunosurveillance Cerebrospinal Fluid Induces Brain Th1 Polarization of T Cells Injected into the
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P170: The Role of Th1 Lymphocytes in The Pathogenesis of Multiple Sclerosis (MS)
Th1 lymphocytes produce cytokines such as IL-2, IFN-γ, and TNF-α, TNF-β and GM-CSF. IFN-γ is the most important Th1 cell cytokine that induces the production of IgG, activation of macrophages, enhancing phagocytosis, and also increasing MHC class I and class II molecules. Increasing serum level of Th1 cytokines have also been observed in MS patients. It has also been prov...
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تاریخ انتشار 2013